insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
This can damage insulin receptors and lead to insulin resistance. — Md Published, Verywell Health, 2 July 2026 As levels dropped, researchers observed signs of frailty, muscle loss, insulin resistance and liver disease in mice. — Kelly McGreal, FOXNews.com, 14 June 2026 People with diabetes or insulin resistance may want to stick with unflavored powder or low-sugar capsules. — Samantha Agate, Miami Herald, 24 June 2026 The findings don’t mean long naps cause liver disease, but that napping might indicate that poor sleep, insulin resistance, or sleep apnea needs attention. — Emily Kay Votruba, EverydayHealth.com, 15 June 2026 See All Example Sentences for insulin resistance

Word History

First Known Use

1927, in the meaning defined above

Time Traveler
The first known use of insulin resistance was in 1927

Rhymes for insulin resistance

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Browse Nearby Words

insulin-like growth factor
insulin resistance
insulin resistance syndrome
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Cite this Entry

“Insulin resistance.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/insulin%20resistance. Accessed 8 Jul. 2026.

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Medical Definition

insulin resistance

noun
: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes
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